PREFACE

TO READERS:

SINCE SIMONE AND I ARE CURRENTLY IN THE MIDDLE OF THIS CAT'S TALE, I INTEND TO PROVIDE A SEMI-CHRONOLOGICAL NARRATIVE IN THIS BLOG.  I'LL START AT THE TIME OF SIMONE'S DIAGNOSIS, WHICH WAS JULY 2009, THEN MOVE FORWARD.  HOWEVER, THERE MAY BE SOME JUMPS BACKWARD TO LOOK AT SOME EARLY HISTORY AND SOME JUMPS FORWARD TO DISCUSS PRESENT SITUATIONS AND EVENTS.  PLEASE NOTE THAT THIS BLOG MOVES FORWARD IN TIME FROM JULY 2009 TO THE PRESENT.  ONCE I GET THROUGH THE NEAR HISTORY, THEN I'LL START A NEW BLOG WITH THE CURRENT EVENTS OF SIMONE'S LIFE AND TREATMENT.  MOST OF THE ACCOUNTS I READ ON THE WEB ABOUT CATS WITH CHRONIC RENAL FAILURE ARE MEMOIRS.  THE SECOND BLOG WILL BE UNIQUE IN THAT IT WILL FOLLOW SIMONE'S LIFE WITH CRF IN REAL TIME.

POSTSCRIPT:  SIMONE'S HEALTH DRAMATICALLY TURNED IN LATE NOVEMBER 2010, AND SHE ENTERED A SLOW DECLINE TOWARDS HER DEATH ON FEBRUARY 15, 2011.  THIS BLOG WAS CONCLUDED ON MARCH 13, 2011.

Final Thoughts

Sunday, March 13, 2011

It has been about a month since Simone was put to sleep.  She is still greatly missed.  Sometimes I'll walk into a room expecting to see her or reach out for her at night while asleep or faintly hear the plaintive sounds only a Siamese can make.

I was curious to see how the other cats, Twinkle Toes (male tuxedo) and Pickles (female tiger), would respond to the loss of Simone.  Since both of them came into the house at different times and were much younger, they never became really close buddies with Simone, but they certainly spent a lot of time with her over the years.  I didn't see any overt signs like sniffing the places where she sacked out or roaming the house in search of her.  But there were other signs of changed behavior.  Both cats became more needy for my attention, followed me around more than usual, and demanded more cuddling.  Twinkle Toes never came into the living room when Fiona, the Boston Terrier, was in there.  Now, he lumbers into the living, jumps on the couch near me, and lays there not even paying attention to the dog.  About two weeks after Simone's death, Twinkle Toes came down with some bad diarrhea.  I could not trace the cause to anything he ate.  Could he have been responding physiologically to the loss?  Who knows?  The problem has slowly resolved itself.  Both cats spend much more time together, both resting and at play.  They have gotten closer to each other.  You can see Twinkles with his arm around Pickles in the recent picture below.  Touching!


In this last post, I want to sum up my experience in living with and treating a cat with chronic renal failure.  First, did I make the right decision in July 2009 to start a treatment program for Simone?  Yes.  I realize that not everyone would make the same decision in similar circumstances.  For me, that decision first came from my heart and then from my head.  So, my initial response was that Simone was a member of my family, a close friend and companion, and I didn't want to lose her.  I knew she was a strong cat and had been healthy her whole life.  I was confident that she would respond favorably to treatment and would be on board with it.  Second, could I do it?  I had not asked that question in the past when other cats had gotten sick; I had simply taken the advice of the vet to euthanize them.  So, I didn't have any experience in administering to a sick cat.  Strangely, I didn't even question myself about taking on those responsibilities.  The first consideration was foremost ... of course I would take care of my 18-year old companion in her final years.  In retrospect, if I knew then what I know now, the decision may not have been made so quickly, but it would been the same decision.

In making that decision, we need to be aware of the time and financial sacrifices that go along with it.  In Simone's case, I spent an extra hour per day treating her, 30 minutes in the morning and in the evening.  I had to adjust my morning and evening routines to accommodate her treatments.  That meant waking up earlier in the morning on work days and coming home in the evenings, even when it was inconvenient.  That meant hiring a pet sitter during vacations who was willing to give subcutaneous injections to maintain proper hydration.  That meant rearranging my leisure time schedule to make sure that Simone got what she needed.  That meant constantly monitoring her condition, researching CRF for alternative treatments, and asking questions.  That meant dealing with the ups and downs of the disease and constantly shifting feelings and worries.

On the financial side, there are significant expenses that accompany the care of a cat with CRF.  Fortunately, for me, the extra expenses were not a burden and they didn't break the bank.   But, that could be a stopper for some people.  In my case, in the approximate 18 months of Simone's treatment, the cost was roughly $2000.  I rationalized the extra expense by realizing how little money I had spent on her health care in the first 18 years of her life.  In prorating the expenses, I spent maybe $125 per year on her health care ... a pretty small amount.  Of course, if you're in a relationship, you need to make sure that your partner is on board with the whole business.

Was it worth it?  You bet.  Simone regained much of her health and the kidney disease remitted for a while.  She was back to her old self for about two-thirds of the treatment period.  We got to spend more time together ... some good, quality time.  We came to terms with her disease (and old age) and had plenty of time to say goodbye.

If it can be of any help to other cat caretakers out there, I've provided links to an Excel workbook that I've maintained over the last 18 months.  It contains a journal, lab work history, a supplies list, and an expenses list.  The two links below are for the 2007 and 2003 versions of Microsoft Excel.  They should also open up in Google Docs.  I'm keeping my fingers crossed that the links will work. 



I want to take a moment to publicly thank my blog followers and all the supporters at Tanya's Feline CRF group and the Feline CRF Support group.  Your words of encouragement, your suggestions, and your condolences were very much appreciated.  All the notes that I received after Simone's passing were wonderful.  If you did not receive a personal reply, know that I read every one of the notes and found solace and comfort in your words.

This is the last post of the Me and Simone blog.  Although this is the end, if there are any readers who have any questions about caring for a cat with CRF, feel free to write by commenting on this post.

Purr on cat lovers!    ><   Mel

"A cat can purr its way out of anything" ( Donna McCrohan)

Au Revoir, My Friend ... Until We Meet Again

On Tuesday afternoon, February 15th, Dr. C. came to my house to euthanize Simone.  I sat next to her and stroked her head as she received a sedative, followed by the lethal drug.  In just moments she was gone, as was her suffering and discomfort.

In Simone's last days, her kidneys were failing her.  She was getting weaker and weaker.  But she still had spirit and awareness.  She still managed to climb the stairs from the basement to the first floor.  She even climbed up the ramp to the bed to spend some time sleeping with Pickles as seen in the picture below.



On Monday morning, after settling in on a bathroom mat, she began to wail, an unusual sound for her.  My wife, unsettled by the sound, decided to stay home from work to keep Simone company throughout the day.  When I came home that evening, Simone was again in the bathroom and wailing intermittently.  As soon as I picked her up, she stopped.  We spent the evening together on the couch in the living room; she was quiet, content, and purred lightly.


 
I fixed a bed for Simone on the basement floor and stayed with her that last night.  She barely made a sound and rested comfortably next to me.  The next morning Simone was so weak that she could not stand up.  She remained in the bed until the afternoon.  Waiting for Dr. C. to arrive, I talked to her about her life, our friendship, and the eternal bond that we had.  She was such a brave and spirited cat.  I felt so fortunate to have had Simone with me for twenty years.

Within an hour of her death, Simone was buried in a leaf compost bed near our house.

I'll miss you Queen Siamese.  In memory of Simone's life:




[There will be one last post in a few weeks time.  In that post, I will summarize my thoughts in taking care of companion pet with a fatal illness like chronic renal failure:  the ups, the downs, the costs, the sacrifices.]

Thanks for reading.  Thanks for your thoughts.  Thanks for your words.  Purr on cat lovers!

Everything
the power of the world
does is done in a circle.  The
sky is round,  and . . . the earth is
round like a ball, and so are all the stars.
The wind, in its greatest power, whirls. Birds
make their nests in circles, for theirs is the same
religion as ours.   The sun comes forth and goes
down again in a circle. The moon does the same,
and both are round.   Even the seasons form a
great circle in their changing and always come
back again to where they were. The life of a
cat is a circle from kitten-hood to kitten-
hood, and so it is in everything
where power moves.
— Black Elk
    (revised)

Time To Say Goodbye?


At the end of winter 2009, I had several dreams about Simone getting sick and dying.  A few months later, she definitely was sick and shortly thereafter got diagnosed with chronic renal failure.  After starting treatment, she came back strong and beat that disease.  Now I think it's old age that has gotten the best of her and there's no beating life's alarm clock.

Last Friday, the news was terrible.  She had lost another pound; her weight was down to 3 lbs 1 oz.  In her youth, Simone was a 7 lb cat, so in just a few months she was down 40% from a healthy weight.  The assisted feeding program was not working.  Her energy was waning.  On Saturday, she had trouble staying on her feet ... wavering, rocking, swaying unsteady as she walked.  Amazingly, she remained alert, still walked around, followed me from room to room, but it became blatantly clear that her quality of life was ebbing away.  She had become incontinent; her physical decline was accompanied by a mental decline.  Simone was letting go very slowly.  As a last ditch effort, I gave her a homeopathic appetite enhancer, but it's probably too late for that.

Tomorrow is a decision day for the last refrain of Simone's journey.  Purr on cat lovers!

"One measure of a good life is the companionship of a devoted cat."  (Mel Weinstein)   

Simone Turns Zombie-Like; The Spiral Continues; We Have A Close Moment



Simone got two full doses of mirtazapine (appetite enhancer) in the previous week.  Although she started to eat small amounts of food in the morning and evening, she became zombie-like after the second dose, which was given 3 days after the first one.  She wasn't craving human flesh, but she was slightly wobbly on her feet, laid on the floor in an odd configuration, stopped talking and purring, looked catatonic (no pun intended), and was just not her old self.  That drug was messing with her brain chemistry!  I decided to stop administering the drug; it took 3 to 4 days for it to clear her body.  If I go back to it, I will have to greatly reduce the dosage.  In the mean time, she returned to not eating any food set out for her, and I continued to assist feed her 2 to 3 times per day.  But, fortunately, her old behaviors returned -- now she walks around more, talks, and, although weak, is more balanced on her feet.

Simone is a disappearing cat ... not in a Cheshire kind of way, but due to continued weight loss.  I took her to the vet's office last Friday, and she had lost another 2.0 oz in a week's time.  That's a 25% weight loss since mid-December.  Not good!  The assisted feeding is not counterbalancing the weight loss ... not sure what to do at this point.  Ugh!!!

A few days ago, after eating a substantial amount of dark chocolate late at night, I was wired at bedtime and couldn't get to sleep.  Around 3:00am I finally gave up, went into the living room, and laid down on the sofa to read a book.  A few minutes later, Simone lopes slowly into the living room, heads over to me, jumps on the couch, and proceeds to lie on my chest, just as she has always done.  In a few minutes, she was purring, which she had not done for at least a week.  I had begun to wonder if the loss of purring was the sign.  She dispelled that idea.  For the time being, Simone was back to her old self, albeit a much smaller version.  What an amazing cat!

Hang onto life as long as you can purr.  So, purr on, cat lovers.

"If you are worthy of its affection, a cat will be your friend, but never your slave." (Theophile Gautier)

The Downward Spiral Continues


On Friday, I took Simone to the vet's office to get a weighing, hoping against my darkest thoughts, that Simone's weight had stabilized since the last visit about one-and-a-half weeks ago.  But she lost even more weight ... about 4 ounces.  She was looking more and more emaciated and frail.  The vet's assistant looked inside her mouth since I was wondering if she might have mouth ulcers, which would cause her to stop eating.  There were no obvious problems inside her mouth.  I listened to the vet's assistant describe the ravages of old age --- the loss of muscle tissue, the inability to chew, the depletion of energy, and so on and so on.  Shit!  I know she was hinting about giving up the struggle, but Simone was still alert, still purring, still talking, still climbing, still jumping, and still sleeping paw-to-paw with me at night.  Simone and I had had the "talk" on several occasions in the last month; I asked her to let me know when she was ready to depart.  Since she had not revealed that to me yet, I remained intent on getting her to eat again and gain some weight.

On Friday, Simone was given the first full dose of mirtazapine.  I had mixed feelings about giving her this medicine since it has been reported in CRF discussion groups that some cats react badly to it and some die from it.  I started her on a half-dose and she seemed to take it okay.  This drug, also used in humans, is a tetracyclic anti-depressant, but the side effects include a reduction in nausea and an increase in appetite.  Also, it can adversely affect heart rate and blood pressure.  On Friday, Simone certainly reacted to the medication as evidenced by her increased energy, dilated eyes, and restlessness, but there was nothing alarming in her reactions.  On the plus side, she followed me around the house, purred excessively, and generally demanded attention.  The drug seemed to elevate her mood.  At the evening meal, she ate about one-third of the food that was set out ... a positive sign.  Of course, that amount of food would not sustain her, so I continued with assisted feeding.

Simone has been getting food by syringe for a few weeks now.  I'm trying to pack as many calories in her as possible at each feeding.  I've experimented with several formulas, but have settled on a combination of Purina NF (very high calorie), tuna with oil, and Gerber chicken or beef baby food.  Using an immersion blender, I combine 8 T. of the Purina NF, 8 T. of tuna, 1 bottle of baby food, and 4 T. of water.  The resultant pudding makes a good mixture for syringing and lasts 3 to 4 days in the fridge.  I estimate that I'm getting about 115 calories in Simone per day, which is a combination of the food blend and Hill's a/d, used to administer the supplements.   Now she's getting a few more calories, maybe 10 to 20, eating food on her own.  That's not bad if she is truly getting about 135 calories per day.  Based on her original weight, Simone should be getting around 180 to 190 calories per day, so I'm hoping with this regimen that Simone's weight loss can be stymied and reversed.

Stay with me cat lovers ... the story continues.  Purr on!!!

"I have studied many philosophers and many cats. The wisdom of cats is infinitely superior."
(Hippolyte Taine)
AT THE BEGINNING OF THIS BLOG, I MENTIONED THAT I WOULD PROVIDE THE HISTORY OF SIMONE'S STORY OF HER STRUGGLE WITH CHRONIC RENAL FAILURE.  AND THAT AT THE END OF THAT STORY, I WOULD START A SEPARATE BLOG CHRONICLING HER LIFE WITH CRF IN REAL TIME.  RECENT EVENTS HAVE CHANGED THAT PLAN.  AT THIS POINT, I WILL END THE HISTORICAL CHRONICLE AND BEGIN THE REAL TIME ONE.  IN LIGHT OF SIMONE'S RECENT HEALTH DECLINE, I FIND IT NECESSARY, IF NOT IMPERATIVE, TO PICK UP HER CURRENT STORY AND FOLLOW IT TO THE END. 

Simone's Condition Nosedives



Sunday, January 23, 2011


Because of recent events, this post will focus on what's happening in the last few months. 

Journal Entry:  November 21, 2010

The vomiting has decreased a little.  Simone vacillates between spending time in the basement and the bedroom.  The basement couch was covered in cheap sheets to keep it from getting stained from vomit if she spends the night there.  Overall, she seems pretty alert and affectionate.  She spends most nights with me in bed.  She still growls and cries for food.  She's not eating as much as usual though, either morning (big meal) or evening, so Twinkles is enjoying the leftovers.  [He's even demanding them now!]

The loss of appetite was a bad sign, but I didn't catch it early on, because the amount of food Simone was eating was decreasing slowly.  She went from gobbling all the food down to three-fourths to one-half to one-quarter, and recently she stopped eating altogether.  I didn't take it as a serious sign because, throughout the treatment for CRF, she had frequently had days when she didn't want to eat much, but she would bounce back a few days later.  By mid-December, I could tell she had lost considerable weight.

I made an appointment with the vet to have her blood checked and to get a physical exam.  As expected, Simone had lost a full pound.  That may not sound like much, but for a 6 1/2 pound cat, that's 15% of her body weight.  The rest of the exam went fine and there weren't any obvious signs why she wasn't eating.  Dr. C. suggested that I give Simone a supplemental food called NutriCal.  This dietary supplement adds calories via corn syrup as well as provides vitamins.  I tried mixing it with Hill's a/d, which was used for the other supplements.  I quickly learned not to like it.  It's a hell of a sticky mess!  It got caught up in Simone's whiskers and other places on her face, where it dried into a nasty crust.  She didn't seem to care for it and that made it easier to stop using it.  After a week, I abandoned the NutriCal.  I particularly didn't like the fact that the extra calories were coming from sugar, as opposed to protein or fat.

There was some good news during this period.  The blood panel showed a strong rebound from the worst signs of CRF.      

Test
Aug  2009 Reading
Norm
Dec 2010 Reading
BUN (mg/dL)
116
12 - 34
42
Creatinine (mg/dL)
6.4
0 - 1.5
2.9
Phosphorus (mg/dL)
6.2
4.0 - 7.0
5.0
Calcium (mg/dL)
12.6
8.4 - 10.8
8.8
Potassium (mg/dL)
3.2
3.8 - 5.0
4.3

Apparently, Simone was not reacting to the CRF ... there was something else wrong.  But Simone continued not to eat much and lost more weight.  The vet suggested trying Purina Fancy Feast kibbles, which she described as "kitty crack."  But Simone took a sniff of the stuff and turned away.  Also, other foods were tried and rejected.  By the second week of January, I was getting extremely concerned.  At that point, I decided to start an assisted feeding program, the details of which will be provided in the next blog.  The goal was to stem the weight loss until a cause could be found.  The vet recommended starting Simone on another appetite stimulant called mirtazapine, and it was ordered from a pharmacy.

One evening, when I was about to give a sub-Q injection of fluid to Simone, she walked over to a nearby litter box and just sat there for several minutes.  Obviously, she was straining to urinate.  Concerned about a bladder infection or blockage, I took her to the vet.  The vet ruled out a blockage but thought she might have a bladder infection.  Also, Simone was frequently sniffling like she had a cold and shaking her head in an odd way.   Simone got a shot of penicillin and, a few days later (Wednesday of this week), she received a more potent antibiotic.  The really bad news was that Simone had lost even more weight ... now she was down to 4.5 lbs (a 31% loss of weight), and she was looking rather gaunt.  I increased the caloric content of the food that she was getting by syringe, and, as of today, I'm keeping my fingers crossed.  Maybe with the elimination of the infection and cold virus, she will start eating again.  On the bright side, Simone continues to move around, purr, and seek attention.  She's still with me!  Stay tuned, cat lovers and purr on!

 "The squirrel that you kill in jest, dies in earnest." (Henry David Thoreau)

Hydration Part 2: Needling Simone


This will be a short post today.  Simone is experiencing some health issues right now ... more about that next week.

It's very important to keep a CRF cat hydrated to flush the kidneys of toxins.  I was lucky to have a cat that stayed calm, cool, and collected during the injection of fluids.  She rarely complained or struggled or ran away, even with my bungling efforts early on.  If you have a cat with CRF, don't be intimidated by this business.  I have no clinical experience, but it didn't take me long to get reasonably adept with the process.  Sure, there were times that I pushed the needle straight through her skin, punctured a vein (blood, yech!), failed to pushed the needle far enough in or pushed it too far in, or needed multiple insertions to get a stick that didn't leak.  Fortunately, these were rare incidents, but I did get frustrated ... some evenings I just gave up.  But that was okay because I'd bounce back the next day and skipping a day really didn't matter that much.  The important thing is to hang in there and stay persistent to provide the best chance for your CRF cat. 

The video above shows a typical sub-cutaneous fluid injection session with Simone.  It's not very instructive, but there are some good websites that explain the process with more clarity and detail.  Here are a few of them:

(pdf article)

(video)

(video)

(video)

(video)

(video)

That's all for today cat lovers.  In the next post, there will be an update on Simone's health.  Purr on cat lovers!

"I began to wonder why we cuddle some animals and put a fork in others.”  (Henry Spira)

Hydration Part 1: Preparing a Sub-Q Bag


Since Simone gets sub-cutaneous fluids every day, I thought that it would be a good idea to show how this is done.  Of course, there are several demonstrations of this procedure on the web, e.g. http://www.fabcats.org/owners/kidney/subcutaneous/info.html.

When my vet's assistant showed me how to administer fluids, they used a demo cat that lived at the clinic.  They assured that the cat would not mind, and, as far as I could tell, it was rather unfazed by the procedure.  I thought to myself that I hoped that the cat didn't have to earn its keep that way.  After the demo, I thought, "Yeah, I can do this.  Looks easy."  When I tried it on Simone, the poor kitty had to endure my clumsiness and ineptitude, and she got overly poked the first few times.  Eventually, with continued practice, I got the hang of it, but there were times when the needle hit a muscle, poked through a fold a skin, or drew blood and I humbly asked Simone's forgiveness.  Occasionally, for some reason, I could not get a good insertion even after 3 tries, and I would give up until the next day.  The point is that, even after learning the technique of sub-Q injections, there are going to be some bad days.  Just hang in there.  Don't beat yourself up.  It will be better the next day.  Fortunately, I was blessed with an easy-going cat, so Simone rarely made a fuzz during my bungling times.  She is very forgiving.

The first part of administering sub-Q fluids is to prepare the bag and delivery pack.  I was hoping that the above video would clearly show this procedure, but it was a shoddy shooting job and the object of interest is sometimes off camera.  So, I will also verbally describe the procedure with some photographic illustrations.  As stated in an earlier blog, I use Lactated Ringers Solution (1 liter) and the delivery kit from Drs. Foster & Smith.
 

#1:  Rip open the outer bag containing the fluids bag and remove it.

#2:  Invert the fluids bag and remove the white, plastic plug.

#3:  Rip open the bag containing the delivery kit.


#4:  Close the thumb-wheel valve by turning the wheel towards the end of the delivery tube.


#5:  Remove the protective cover from the plastic spike at the upper end of the delivery tube.
#6:  Insert the spike into the bottom of the fluids bag.


#7:  Lift the fluids bag upright (no fluid should flow), and squeeze the clear, plastic tube until it half fills with fluid.
#8:  Hang the bag with the delivery tube in a convenient location for administering fluids.


#9:  Remove the cap at the end of the delivery tube and attach a sterile syringe.


That's it feline fanciers.  In the next post, I'll publish part 2 of hydration.  Purr on cat lovers!
 
"A cat has absolute emotional honesty: human beings, for one reason or another, may hide their feelings, but a cat does not.(Ernest Hemingway)